UC Davis Startup Evolve BioSystems Announces Results of Clinical Study

baby holding mothers finger

Evolve BioSystems, Inc., a spin-off from the UC Davis Foods for Health Institute (FFHI) that is developing novel solutions to restore and maintain a healthy newborn gut microbiome, announced today the outcome of its clinical study evaluating the probiotic product B. infantis EVC001 in breast-fed infants.  In its press release, the company stated that the study showed that providing dietary B. infantis EVC001 resulted in rapid, substantial, and persistent remodeling of the gut microbiome in breastfed infants, leading to a reduction in the amount of potentially harmful bacteria.

Evolve’s founding team, which includes UC Davis faculty members Bruce German, David Mills, Carlito Lebrilla and Daniela Barile, along with former FFHI Assistant Director Samara Freeman, has been conducting research at the forefront of infant nutritional health for over a decade, focusing on the key role that breast milk plays in creating a healthy intestinal tract. The company is led by nutrition and health industry veterans Timothy Brown, the company’s CEO, and David Kyle, the company’s Board Chairman and Chief Scientific Officer.

“These results with B. infantis EVC001 demonstrate for the first time that when the appropriate probiotic bacteria are provided in combination with breast milk, they can rapidly and stably colonize the infant gut microbiome while significantly reducing levels of potentially harmful bacteria linked to long-term disease,” said Mark Underwood M.A.S., M.D., Chief of Pediatric Neonatology and Professor of Pediatrics at the University of California Davis, and a principle investigator on the study. “This study is extremely important for infant health and nutrition because we may now have the potential to impact many common health issues by simply restoring the microbiome to its natural state.”

”We are thrilled to see the successful translation of university research into beneficial health outcomes for infants with the potential to persist into later life,” said Dushyant Pathak, associate vice chancellor of Research and executive director of Venture Catalyst at UC Davis. “This success is particularly heartening given the close working relationship developed with the company and support provided by the InnovationAccess and Venture Catalyst teams at UC Davis”

View Evolve’s press release for more information.